Recombinant Mouse BMP-8a Protein INQUIRY

Cat.No: RP-2004M
Cat# RP-2004M
Product Name Recombinant Mouse BMP-8a Protein
Synonym OP2; OP-2; Bmp7r1
Background BMP8, also known as osteogenic protein 2 (OP2), was first isolated from a hippocampal library in a screen to identify relatives of BMP7/OP1. BMPs are a family of structurally and functionally related proteins and represent a subfamily of the transforming growth factor beta (TGFbeta ) superfamily. BMPs are involved in a wide range of processes including embryogenesis, tissue morphogenesis, cell differentiation and migration, and tumorigenesis. Cellular responses to BMPs are mediated by heterooligomeric complexes of type I and type II serine/threonine kinase receptors. BMP8a and BMP8b, produced from separate genes, share 98% amino acid sequence identity in human but only 74% in mouse within the mature regions.
Source CHO
Molecular Characterization Predicted Molecular Mass15.7 kDa (monomer), 19 kDa, reducing conditions
Predicted N Terminal Ala261
Endotoxin < 0.1 EU/μg, determined by LAL method.
Purity Greater than 95% as analyzed by SDS-PAGE.
Formulation Lyophilized from a 0.2 μm filtered solution in HCl.
Reconstitution Reconstitute at 250 μg/mL in 4 mM HCl.
Bioactivity Active
Storage This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
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