Freund’s Adjuvant INQUIRY

Cat.No: CFA-102
Cat#: CFA-102   Complete Freund’s Adjuvant (CFA)
Cat#: ICFA-103   Incomplete Freund’s Adjuvant (ICFA)

Size: 500mL

Description:
 

Adjuvant is used to stimulate and enhance the immune response to an immunogen. By mixing the immunogen with the adjuvant to form a stable emulsion, a sustained presentation of the antigen is achieved. This depot effect results in improved immune response and higher serum antibody levels. Freund's complete adjuvant(CFA) is effective in stimulating cell-mediated immunity and leads to potentiation of T helper cells that leads to the production of certain immunoglobulins and effector T cells.
 
Incomplete Freund’s adjuvant (ICFA) is one of the most commonly used adjuvants in research. It is prepared from non-metabolizable oils. IFA can be used to produce water-in-oil emulsions of antigens. ICFA induces a predominantly Th2-biased response through the formation of a depot at the injection site and the stimulation of antibody producing plasma cells.
 
Freund’s adjuvant consists of a mixture of mineral oil and an emulsifier mannide monooleate. Complete Freund’s Adjuvant contains 1 mg/ml heat-killed and dried Mycobacterium tuberculosis H37Ra. The mycobacteria stimulate the immune system and enhance the immune response.  1mL Incomplete Freund’s Adjuvant contains 0.85 ml paraffin oil and 0.15 ml of mannide monooleate.

Storage: Freund’s Adjuvant
is shipped at ambient temperature and stored at 2-8ºC (Do not freeze!). The adjuvant is stable for up to 3 years at 2-8ºC.
 


 
 
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